Projects
Our work is divided into three sub-projects. On this page you can find out what we are doing and what our goals are.
Project 1:
Method development and network description
- Identification and description of typical network characteristics of psychopathology, neurobiological processes and psychological mechanisms from existing data sets.
- Investigation of the stability and change of dynamic networks.
- Identification of variable sets that seem particularly fruitful for network analyses.
- Development and further development of statistical analysis approaches for various network models.
- Establishment of novel machine learning methods for improved predictions of disease progression.
Project 2:
Collection of longitudinal network data
- Establishment of a standardized measurement protocol for a baseline observation phase in adult patients.
- Continuous recruitment to expand the database using the measurement protocol.
- Provision of data from the adult cohort for further analysis for all subprojects.
- Modeling of dynamic networks in healthy adults and patients as part of various projects.
- Development of new measurement instruments to study social behavior in children and adolescents.
- Modeling dynamic networks of typical and deviant developmental patterns in children and adolescents.
- Establishment of a cross-site database of network data in children and adolescents.
- Characterization of changes in neurobiological, psychological and pathopsychological networks in post-traumatic stress and after psychotherapy.
Project 3:
Experimental studies on network change
- Establishment of paradigms for the experimental psychological, pharmacological and neurostimulatory alteration of networks.
- Evaluation of the corresponding changes in monotherapy.
- Analysis of therapy response patterns and predictors of therapy response, also in combination treatments (e.g. psychotherapy and antidepressant administration).
- Exploration of psychological and neurobiological network changes through placebo and nocebo effects
- Research into the therapeutic usefulness of expectation and placebo effects.
